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Showing posts with label Diabetes. Show all posts
Showing posts with label Diabetes. Show all posts

Monday, October 20, 2008

Why Does Colorado Kick Alabama’s Fat Butt?

By Scott Mowbray

Alabama resident and Health.com diabetes blogger Sean Kelley has worked hard to put his home state’s obesity rank (No. 2 in the country, waddling just behind Mississippi) in context. Don’t snicker at the deep-fried South, Sean warns: “The South may have the three states that have obesity rates of more than 30%, but the rest of the country (save Colorado) is not far behind with rates between 20% and 29%.”

I’ve lately been spending time in Colorado, the only state whose obesity rate, at 18.7%, weighs in below 20%. (Obesity is defined as having a Body Mass Index, or BMI, greater than 30). And I can tell you that as a New Yorker who carries 20 extra pounds around, I’m anxious when I walk into a Colorado social event. Will I be the porkiest guy in the room? Usually, yes. About 80% of the people at any gathering I’ve been to in Colorado are Obama-thin (especially the Republicans) and have that calm-before-the-void look that comes from knowing the difference between a piton and a carabiner. Read More

Wednesday, September 10, 2008

Air Pollution Harms Patients After Heart Attack

(HealthDay News) -- Tiny particles in air pollution can harm people with coronary artery disease by crippling the ability of the heart to conduct electrical signals, Harvard University researchers report.

Pollution from cars and trucks and industrial plants has been shown to trigger heart attacks, but exactly how it does that hasn't been well-known, researchers say.

"We found that elevation in fine particles from non-traffic as well as traffic sources and black carbon, a marker for traffic, predicted depression ST-segment levels," said lead researcher Dr. Diane R. Gold, an associate professor of medicine and environmental health. "Effects were greatest within the first month after hospitalization and for patients with heart attack during hospitalization or with diabetes."

The report is published in the Sept. 9 online edition of Circulation.

For the study, Gold's team collected data on 48 patients from the Boston area with coronary artery disease. The researchers monitored the patients for 24 hours using portable electrocardiograph machines looking for changes in the electrical conductivity of the heart called ST-segment depression. This dysrhythmia can indicate inadequate blood flow to the heart or inflammation of the heart muscle.

All patients had been hospitalized for heart attack, unstable angina or worsening symptoms of coronary artery disease. Forty percent had suffered heart attacks, and 25 percent had diabetes.

Gold's group also looked at the average 24-hour levels for all pollutants in Boston. They found that these levels were below accepted or proposed National Air Quality Standard thresholds.

The researchers found that increased levels of a pollutant called PM 2.5 and black carbon, which is found in traffic exhaust, was associated with an increase in ST-segment depression.

In addition, sulfur dioxide, which is the product of combustion, but not from cars, was also associated with an increase in ST-segment depression.

Increases in ST-segment depression were particularly higher in patients recovering from a heart attack compared with other patients, the researchers reported.

"If the air pollution-associated ST-segment changes represent either myocardial inflammation or risk of ischemia, then it is possible that reduction in regional traffic and non-traffic associated air pollution may reduce heart attack or risk for either ischemia, arrhythmia or heart failure in patients with coronary artery disease in the period after hospitalization," Gold said.

For patients who have just been discharged from hospital after a heart attack, guidelines from the American Heart Association and the American College of Cardiology suggest that patients should avoid heavy traffic because of the stress of driving, Gold said.

"Our study provides additional rationale to avoid or reduce heavy traffic exposure after discharge, even for those without a completed myocardial infarction, since traffic exposure involves pollution exposure as well as stress," Gold said.

Dr. Byron Lee, a cardiologist at the University of California, San Francisco, agrees that patients who have had a recent heart attack should avoid air pollution.

"This study provides very strong evidence that environmental pollution puts added stress on the heart," Lee said. "Patients who have just had a heart attack should probably do what they can to avoid pollution exposure. This may mean staying indoors during smoggy days or getting out of the city altogether."

Dr. Samin Sharma, director of interventional cardiology at Mount Sinai Medical Center in New York City, thinks that patients who have suffered a recent heart attack and live in areas where air pollution levels are high and unavoidable need to be monitored more carefully.

"Maybe these patients need close follow-up," Sharma said. "These patients may need an increase in their heart medications or medications need to be changed. Optimal aggressive medical therapy and optimization of medical care could be the answer for these patients."

More information
For more on air pollution and heart disease, visit the American Heart Association.

Thursday, July 31, 2008

Herbal Detox Formulas

If you follow the lifestyle of the majority of the population in the United States bad diet, little exercise, stressful lifestyle–you have a 50 percent chance of contracting a major disease such as cancer, arthritis, arteriosclerosis, heart disease, diabetes, or AIDS. It’s crucial to learn how to detoxify remove all the toxins that have accumulated in your body and let your fluids and tissues regenerate. Continue Reading >>

Wednesday, July 30, 2008

Can Fruit Juice Be Worse Than Soda?

By Sean Kelley

Which of the following contains more calories and more carbohydrates?

A. Apple juice
B. Coca-Cola


This is the kind of Nutrition 101 question that a nurse educator posed to me after I was diagnosed with diabetes. I remember it well because I was startled by the answer: Read More

Tuesday, July 22, 2008

The Secret To Health - Part 8 of 8

The Secret to Health reveals information that has been suppressed by the medical establishment for over 100 years! Learn how you can restore your health, increase your energy and vitality, and take control of your body again!



More informations here:

more discussion: Forum· Addiction Forum · Ask the Doctors Forum · Ayurveda Forum · Ayurvedic & Thai Herbs Forum · Colon Cleansing Forum · Dental Forum · Diabetes Forum · Diet Forum · General Cleansing Forum · Hepatitis A, B. C Forum · Integrated Medicine Forum · Live Blood Analysis Forum · Ozone-Oxygen-Forum · pH - Alkaline - Acidity Forum · Weight Loss Forum



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Monday, July 21, 2008

The Secret To Health - Part 7 of 8

The Secret to Health reveals information that has been suppressed by the medical establishment for over 100 years! Learn how you can restore your health, increase your energy and vitality, and take control of your body again!



More informations here:

more discussion: Forum· Addiction Forum · Ask the Doctors Forum · Ayurveda Forum · Ayurvedic & Thai Herbs Forum · Colon Cleansing Forum · Dental Forum · Diabetes Forum · Diet Forum · General Cleansing Forum · Hepatitis A, B. C Forum · Integrated Medicine Forum · Live Blood Analysis Forum · Ozone-Oxygen-Forum · pH - Alkaline - Acidity Forum · Weight Loss Forum



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Top Quality Colon Cleansing
Oxy-Powder® is a scientifically formulated compound that uses the power of oxygen to safely aid the body in relieving irritation associated with constipation symptoms. A clean, toxin-free intestinal tract is the foundation for maintaining optimal health. Did you know over 100 million Americans are constipated? 120 Vegetarian Capsules.

Sunday, July 20, 2008

The Secret To Health - Part 6 of 8

The Secret to Health reveals information that has been suppressed by the medical establishment for over 100 years! Learn how you can restore your health, increase your energy and vitality, and take control of your body again!



More informations here:

more discussion: Forum· Addiction Forum · Ask the Doctors Forum · Ayurveda Forum · Ayurvedic & Thai Herbs Forum · Colon Cleansing Forum · Dental Forum · Diabetes Forum · Diet Forum · General Cleansing Forum · Hepatitis A, B. C Forum · Integrated Medicine Forum · Live Blood Analysis Forum · Ozone-Oxygen-Forum · pH - Alkaline - Acidity Forum · Weight Loss Forum



Oxy-Powder®

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$42.95
[ learn more ]

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Top Quality Colon Cleansing
Oxy-Powder® is a scientifically formulated compound that uses the power of oxygen to safely aid the body in relieving irritation associated with constipation symptoms. A clean, toxin-free intestinal tract is the foundation for maintaining optimal health. Did you know over 100 million Americans are constipated? 120 Vegetarian Capsules.

Saturday, July 19, 2008

The Secret To Health - Part 5 of 8

The Secret to Health reveals information that has been suppressed by the medical establishment for over 100 years! Learn how you can restore your health, increase your energy and vitality, and take control of your body again!



More informations here:

more discussion: Forum· Addiction Forum · Ask the Doctors Forum · Ayurveda Forum · Ayurvedic & Thai Herbs Forum · Colon Cleansing Forum · Dental Forum · Diabetes Forum · Diet Forum · General Cleansing Forum · Hepatitis A, B. C Forum · Integrated Medicine Forum · Live Blood Analysis Forum · Ozone-Oxygen-Forum · pH - Alkaline - Acidity Forum · Weight Loss Forum



Oxy-Powder®

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Top Quality Colon Cleansing
Oxy-Powder® is a scientifically formulated compound that uses the power of oxygen to safely aid the body in relieving irritation associated with constipation symptoms. A clean, toxin-free intestinal tract is the foundation for maintaining optimal health. Did you know over 100 million Americans are constipated? 120 Vegetarian Capsules.

Friday, July 18, 2008

The Secret To Health - Part 4 of 8

The Secret to Health reveals information that has been suppressed by the medical establishment for over 100 years! Learn how you can restore your health, increase your energy and vitality, and take control of your body again!



More informations here:

more discussion: Forum· Addiction Forum · Ask the Doctors Forum · Ayurveda Forum · Ayurvedic & Thai Herbs Forum · Colon Cleansing Forum · Dental Forum · Diabetes Forum · Diet Forum · General Cleansing Forum · Hepatitis A, B. C Forum · Integrated Medicine Forum · Live Blood Analysis Forum · Ozone-Oxygen-Forum · pH - Alkaline - Acidity Forum · Weight Loss Forum



Oxy-Powder®

Oxy-Powder®

$42.95
[ learn more ]

Add to Cart

Top Quality Colon Cleansing
Oxy-Powder® is a scientifically formulated compound that uses the power of oxygen to safely aid the body in relieving irritation associated with constipation symptoms. A clean, toxin-free intestinal tract is the foundation for maintaining optimal health. Did you know over 100 million Americans are constipated? 120 Vegetarian Capsules.

The Secret To Health - Part 3 of 8

The Secret to Health reveals information that has been suppressed by the medical establishment for over 100 years! Learn how you can restore your health, increase your energy and vitality, and take control of your body again!



More informations here:

more discussion: Forum· Addiction Forum · Ask the Doctors Forum · Ayurveda Forum · Ayurvedic & Thai Herbs Forum · Colon Cleansing Forum · Dental Forum · Diabetes Forum · Diet Forum · General Cleansing Forum · Hepatitis A, B. C Forum · Integrated Medicine Forum · Live Blood Analysis Forum · Ozone-Oxygen-Forum · pH - Alkaline - Acidity Forum · Weight Loss Forum



Oxy-Powder®

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$42.95
[ learn more ]

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Top Quality Colon Cleansing
Oxy-Powder® is a scientifically formulated compound that uses the power of oxygen to safely aid the body in relieving irritation associated with constipation symptoms. A clean, toxin-free intestinal tract is the foundation for maintaining optimal health. Did you know over 100 million Americans are constipated? 120 Vegetarian Capsules.

Tuesday, July 15, 2008

The Secret To Health - Part 2 of 8

The Secret to Health reveals information that has been suppressed by the medical establishment for over 100 years! Learn how you can restore your health, increase your energy and vitality, and take control of your body again!




More informations here:

more discussion: Forum· Addiction Forum · Ask the Doctors Forum · Ayurveda Forum · Ayurvedic & Thai Herbs Forum · Colon Cleansing Forum · Dental Forum · Diabetes Forum · Diet Forum · General Cleansing Forum · Hepatitis A, B. C Forum · Integrated Medicine Forum · Live Blood Analysis Forum · Ozone-Oxygen-Forum · pH - Alkaline - Acidity Forum · Weight Loss Forum



Oxy-Powder®

Oxy-Powder®

$42.95
[ learn more ]

Add to Cart

Top Quality Colon Cleansing
Oxy-Powder® is a scientifically formulated compound that uses the power of oxygen to safely aid the body in relieving irritation associated with constipation symptoms. A clean, toxin-free intestinal tract is the foundation for maintaining optimal health. Did you know over 100 million Americans are constipated? 120 Vegetarian Capsules.

Monday, July 14, 2008

The Secret To Health - Part 1 of 8

The Secret to Health reveals information that has been suppressed by the medical establishment for over 100 years! Learn how you can restore your health, increase your energy and vitality, and take control of your body again!

90% of Disease is Caused by Toxins Entering the Body!

Every single day, your body absorbs millions of toxins from Ngenetically modified foods, pesticides, meat, dairy, soy, white flour, table salt, MSG (monosodium glutamate), microwaved foods, refined sugar, and artificial sweeteners. You also receive toxins from caffeine, alcohol, electromagnetic radiation, heavy metals, parasites, industrial chemicals, and prescription drugs. These impurities contaminate nearly everything we eat, drink, touch, or breathe and they are the root cause of disease!

Did You Know? * You should have three bowel movements every day, not two or three per week! * Constipation and other digestive disorders afflict 1 out of every 5 people in America, with the average person carrying up to 15lbs of impacted waste in their colon ! * Experts estimate 9 out of 10 people have parasites in their bodies and don't know it! * Playing on a typical floor exposes babies' lungs to the equivalent of four cigarettes in the form of contaminants from mold, mildew, and dust mites! * Most pharmaceutical drugs list constipation as a major side effect! * Unnecessary medical procedures and prescription drug use in the U.S. accounts for over 700,000 deaths annually!




More informations here:

more discussion: Forum· Addiction Forum · Ask the Doctors Forum · Ayurveda Forum · Ayurvedic & Thai Herbs Forum · Colon Cleansing Forum · Dental Forum · Diabetes Forum · Diet Forum · General Cleansing Forum · Hepatitis A, B. C Forum · Integrated Medicine Forum · Live Blood Analysis Forum · Ozone-Oxygen-Forum · pH - Alkaline - Acidity Forum · Weight Loss Forum



Oxy-Powder®

Oxy-Powder®

$42.95
[ learn more ]

Add to Cart

Top Quality Colon Cleansing
Oxy-Powder® is a scientifically formulated compound that uses the power of oxygen to safely aid the body in relieving irritation associated with constipation symptoms. A clean, toxin-free intestinal tract is the foundation for maintaining optimal health. Did you know over 100 million Americans are constipated? 120 Vegetarian Capsules.

Tuesday, June 03, 2008

High-Calorie Sports Drink Ruins Exercise Benefit

By Sean Kelley

Usually when my blood sugar spikes above 300 (normal is 80 to 120), I blame lack of exercise or dietary exuberance. If my type 2 diabetes is out of control, it’s because I made poor but conscious choices that led to higher counts.

Last week, when my sugar shot high, exercise—not the lack of it—was to blame.

I’m not sure what possessed me to join a flag football league. I’m way past my prime and not in very good shape. But there I was trying to keep up with younger, more athletic men, sweating out what little energy I had under a hot, 90-degree Southern sun. Read More

Sunday, March 16, 2008

What is a "Kidney Cleanse" ?

A Kidney cleanse is a procedure aimed at dissolving Kidney stones - stones formed inside kidneys.

Kidney cleanse can also be used for improving kidney health by flushing out toxins accumulated inside kidney tissues.

There are many different kinds of Kidney stones. Sometimes, it can take days to dissolve them, sometimes it can take months. Sometimes, water is enough, sometimes, you may need several different remedies.

Crystals form in urine from various salts that build up on the inner surfaces of the kidney. Eventually these crystals become large enough to form stones in the kidney (called nephrolithiasis).

Such salts may include calcium oxalate, uric acid, cystine, or xanthine. These salts can become extremely concentrated under certain circumstances: if the volume of urine is significantly reduced (chronic thirst and dehydration); or if abnormally high amounts of crystal-forming salts are present (infection). When concentration levels reach the point at which the salts no longer dissolve, they precipitate out and form crystals.

Stones may also form in the ureter or the bladder. The salts that form these stones are made up of combinations of minerals and other chemicals, some of which are derived from a person's diet.

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Monday, December 31, 2007

Men Who Smoke Prone to Impotence

(HealthDay News) -- If heart disease, stroke and certain cancers haven't been reason enough for men to quit smoking, consider this: The habit also increases the risk of erectile dysfunction.
In fact, emerging research shows that men with a pack-a-day habit are almost 40 percent more likely to struggle with erectile dysfunction than men who don't smoke.

"Smoking delivers nicotine and other vasoconstrictors that close down the blood vessels" of the penis, explained Dr. Jack Mydlo, chairman of urology at Temple University School of Medicine and Hospital in Philadelphia.

Erectile dysfunction -- also called "ED" or impotence -- is the inability to achieve or sustain an erection on repeated occasions. It's estimated that about two of every 100 American men have erectile dysfunction serious enough to warrant a doctor's visit, according to the U.S. National Institute of Diabetes and Digestive and Kidney Disorders. As men age, the risk of erectile dysfunction increases.

A recent study of more than 8,000 Australian men between the ages of 16 and 59 found that those who smoked less than a pack a day had a 24 percent increased risk of erectile problems. And, as the number of cigarettes smoked went up, so, too, did the chances of erectile dysfunction. Those men who averaged more than 20 cigarettes a day increased their risk of erectile dysfunction by 39 percent, reported the study, published in the journal Tobacco Control.

Another study, this one published in the American Journal of Epidemiology, found that male smokers in their 40s were more likely to experience erectile difficulties than older nonsmoking males. The risk of erectile dysfunction was nearly doubled for smoking men in their 40s compared to nonsmokers in their 50s.

"Smoking, because it causes blood vessel constriction, is a very big cause of erectile dysfunction," said Dr. Larry Lipshultz, chief of male reproductive medicine at Baylor College of Medicine in Houston.

Smoking isn't the only cause of impotence problems -- other lifestyle habits can have a big impact on men's sexual health. Obesity, heavy alcohol consumption and recreational drug use can all cause erectile dysfunction. And a sedentary lifestyle can also contribute to erectile problems, Lipshultz added.

Other causes include diabetes; heart disease; cancer surgery of the prostate, bladder, colon or rectum; high blood pressure medications or antidepressants; a spinal injury; and a hormone imbalance, usually low testosterone, Lipshultz explained.

All of these conditions or lifestyle factors contribute to erectile difficulties in three major ways: By reducing blood flow, causing nerve damage, or changing the hormonal environment.
While there are medications that can help treat erectile dysfunction, both Mydlo and Lipshultz advocated a healthy lifestyle for maintaining good sexual health.

"Take better care of yourself. Make sure you're not obese, eat well, exercise, and if you have diabetes or hypertension, make sure they're well-controlled," advised Lipshultz, who added that by addressing lifestyle factors, you may not need medication to treat erectile dysfunction.

Mydlo echoed that advice, adding, "Stop smoking, drink in moderation, lose weight, and maintain good blood pressure."

Mydlo added one more word of caution: "Don't use ED medications -- Viagra, Cialis -- if you don't need them. Erections that last longer than four hours -- priapism -- can cause permanent scar tissue and permanent impotence. It's not a good idea to use these drugs casually."

More information
To learn more about erectile dysfunction and how to prevent it, visit the National Institute of Diabetes and Digestive and Kidney Diseases.

Friday, December 28, 2007

Health Tip: What's Causing Your Dizziness?

(HealthDay News) - Dizziness is not a disease, but a symptom of another condition. While it's usually not serious and is often temporary, it helps to know what's causing the problem.

The University of Michigan Health System lists these common causes of dizziness:
  • An infection or other condition affecting the inner ear.
  • Fatigue, stress or fever.
  • Low blood sugar.
  • Anemia.
  • Dehydration.
  • An injury to the head.
  • A heart or circulatory condition.
  • Stroke.
  • A side effect of certain medications.

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Tuesday, December 25, 2007

Beware Holiday Toys That Can Injure Young Eyes

(HealthDay News) -- While concern about lead in toys has attracted a great deal of attention lately, it's just one of the potential dangers that toys may pose to children. For example, some toys can damage children's eyes, warns the American Academy of Ophthalmology (AAO).

There were more than 210,000 toy-related injuries treated in U.S. emergency rooms in 2005, and about 6,000 of those involved injuries to the eyes of children under age 15, according to the federal Consumer Product Safety Commission.

"The holidays are supposed to be a time of happiness and celebration. A serious eye injury can bring an abrupt end to the celebration. Parents should choose a toy that is appropriate for their child's age, abilities, maturity, and the parent's willingness to supervise use of the toy," Dr. David Coats, clinical correspondent for the AAO and a pediatric ophthalmologist at Texas Children's Hospital in Houston, said in a prepared statement.

BB guns, darts, pellet guns and paintball guns are among the toys that pose a threat to the eyes.
"Any toy that can eject or propel an object can lead to a serious eye injury if used incorrectly.

This includes innocuous appearing toys such as a popgun or a paddleball set," Coats said.

He also said children who receive sports equipment as gifts should be given protective eyewear.

"If you plan to give sports equipment, provide appropriate protective gear, such as helmets, facemasks or goggles with polycarbonate lenses," Coats said.

More information
Safe Kids USA has more about toy-related injuries.

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Friday, December 21, 2007

Sex Ed Does Delay Teen Sex: CDC

(HealthDay News) -- Sex education programs do work to help discourage many teens from becoming sexually active before age 15, according to data released Wednesday by the U.S. Centers for Disease Control and Prevention (CDC).

Formal programs -- such as those presented in schools and church groups -- did appear to delay onset of sexual activity. For example, teen girls in the nationally representative sample were 59 percent less likely to start having sex before age 15 if they had received sex education, while teen boys were 71 percent less likely, the study found.

"We were obviously hoping to find that sex education is effective. We're glad to see the strong associations," said lead author Trisha Mueller, a CDC epidemiologist. She emphasized that in order to be successful, sex education should take place before young people become sexually active.

Mueller's team also learned that teen boys who attended school were almost three times more likely to use contraception if they had attended a sex education program, compared to those who had not.

However, attendance at a sex education class did not seem to impact girls' use of birth control, the survey found.

The survey did not differentiate between programs that emphasized abstinence and those that educated about contraception. Instead, researchers focused only on whether the teens had ever attended any sex education program in a formal setting, such as school or church.

The study was expected to be published in the January issue of the Journal of Adolescent Health.

According to earlier, 2005 data available from the CDC, 47 percent of high school students said they had already had sex. Of those who were currently involved in a sexual relationship, one-third said they were not using a condom.

Curious about the effectiveness of sexual education on these behaviors, Mueller and colleagues examined data from more than 2,000 teen boys and girls between 15 and 19 years of age who participated in the door-to-door 2002 National Survey of Family Growth.

"Formal sex education is beneficial for youth who are considered to be at-risk," noted Mueller, who cited as an example the 88 percent reduced risk of initiation sex before age 15 among urban black females who had received any sex education. Urban black teen girls who were still in school at the time of the survey had a 91 percent reduced risk of initiation sex before age 15, the survey found.

The research also showed that boys living in single-parent households were more likely to delay sex past age 15 if they had attended a sex education class.

Mueller and her team were interested in teen sexual decision-making before and after the age of 15, because the federal governments' Healthy People 2010 initiative treats 15 as a dividing line. Healthy People 2010 sets a wide array of health goals for states and communities to achieve over the first decade of this century. One of its objectives: to reduce the number of teens under age 15 who are having sex for the first time.

"First and foremost, the report makes clear that the timing of sex education is quite important. That is, providing sex education to young people at an early age seems quite important in helping delay sexual activity," said Bill Albert, deputy director of the Washington, D.C.-based National Campaign to Prevent Teen and Unplanned Pregnancy.

The researchers said the study could not explain why sex education might have a stronger effect in delaying sex among teen boys and black girls, but Albert offered an explanation.

"It is the case that declines in sexual activity among teen boys, as opposed to girls, and African-American teen girls, as opposed to other racial/ethnic groups, have been much more dramatic over the past decade. This may, in part, explain why the effect of sex education seems stronger. It may also be that concern about HIV/AIDs may be particularly strong among these two groups," said Albert.

However, certain sub-populations of teens deserve further research, said Mueller. The data suggested that both rural, white teen girls and white or Hispanic teen girls who had dropped out of school might be more likely to have sex before age 15 if they had sex education, but Mueller said the number of people in those groups in the study was so small that the results could be a statistical fluke.

"They were kind of opposite findings," said Mueller, who acknowledged that "some subgroups may not benefit from sex ed the same way as the larger group of teens."

This research comes in the wake of data released Dec. 5 by the CDC showing that the annual rate of births to teens has increased for the first time in 14 years. Between 2005 and 2006, the birth rate for girls 15 to 19 rose 3 percent -- from 40.5 births per 1,000 in 2005 to 41.9 per 1,000 in 2006.

Considering both studies, Albert said, "The early wins may have been won. Future efforts may well have to be more intense, focused, and creative if the nation is to make continued progress in reducing teen pregnancy and childbearing. Put another way, yesterday's way of doing business will no longer suffice."

More information
To find more data about teenagers and sexual decision-making, visit the U.S. Centers for Disease Control and Prevention.

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Sunday, December 02, 2007

Extra Doses of Vitamins C, E Don't Guard Against Preeclampsia

(HealthDay News) -- Taking extra doses of vitamins E and C doesn't reduce the chances of the blood pressure disorder preeclampsia in women who are at risk for the dangerous pregnancy complication, a new report finds.

The study casts real doubt on the effectiveness of this regimen in preventing preeclampsia, said study author Dr. Joseph A. Spinnato II, a professor of obstetrics and gynecology at the University of Cincinnati College of Medicine. "There were those that were arguing that the evidence was enough prior to our publication, so I think this is added weight," he said.

There may be other avenues of hope, however.

"The article was compelling and a little disappointing, but the authors left us with an out at the end of the article, that perhaps we shouldn't give E and C at the same time because the E might negate the C," said Dr. Miriam Greene, an assistant professor of obstetrics and gynecology at New York University School of Medicine in New York City. "You can continue and try to do the two separately. They did prove that the drugs were safe."

The findings appears in the December issue of Obstetrics & Gynecology.

Preeclampsia, which occurs in about 5 percent of all pregnant women in the United States, can lead to sudden high blood pressure and irregular blood flow. This can activate platelets and the clotting system, which in turn slows blood flow further.

Risk factors for preeclampsia include: first pregnancy, 10 years since previous pregnancy, carrying multiple fetuses, being overweight, being under 20 or over 35, or having a history of high blood pressure, diabetes, kidney disease, lupus or preeclampsia in a previous pregnancy, according to the March of Dimes.

At present, medical professionals have no clear guidance on how to prevent this potentially fatal condition.

"We don't have a good way to reduce the incidence of preeclampsia, except in calcium-deficient populations and those tend not to be in the U.S.," Spinnato said. "There is some evidence that still supports the use of baby aspirin among patients at risk, but even that is argued pretty heavily."

An Australian study published last year also found no benefit to vitamin C and E supplementation.

The current study involved 707 women at four Brazilian sites who were in their second trimester of pregnancy and who had chronic hypertension or a prior history of preeclampsia.
The women were randomly assigned to receive 1,000 milligrams of vitamin C with 400 International Units of vitamin E or a placebo daily.

The rate of preeclampsia was 13.8 percent in the vitamin group and 15.6 percent in placebo group, which was not a statistically significant difference.

There appeared to be no harmful effects on the fetus, a finding echoed in previous trials.
But this study had one surprise finding: more frequent premature rupture of membranes among women taking vitamins. "That was completely unexpected," said Spinnato, who is following up on the finding.

Other than the possibility that vitamin E is canceling out vitamin C, there is no clear explanation for why the combination didn't work.

"One of the continuing challenges to vitamin supplementation as a general thing is getting it from leafy vegetables is different than getting it from a pill," Spinnato said. "There are also those who argue that we didn't start [giving the vitamins] early enough, but that argument is difficult to swallow. There are medical and legal ramifications even for vitamins."

More information
To learn more about preeclampsia, visit the March of Dimes.

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Wednesday, November 28, 2007

Low Testosterone Might Shorten Men's Lives

(HealthDay News) -- Men aged 40 or over with low levels of testosterone may be at increased risk of fatal heart attacks or death from any cause, a British study suggests.

In fact, "The magnitude of the effect was very similar to that of [high] cholesterol or blood pressure," said lead researcher Dr. Kay-Tee Khaw, professor of clinical gerontology at the University of Cambridge School of Clinical Medicine.

However, more work is needed to see whether testosterone supplements should be recommended for men with naturally low levels of the hormone, she said.

"We need to replicate these findings," Khaw said. "We hope we can entice other investigators to look at testosterone levels and see if these findings are confirmed."

Her team published the findings in the Nov. 27 issue of Circulation.

The study included more than 11,600 men ages 40 to 79 who were free of known cardiovascular disease and cancer at the start of the trial. It was done because "there have been lots of studies suggesting that low testosterone may not be good for health," Khaw said. "So, we wanted to see if this could be demonstrated in a large population. Testosterone is hard to measure, the test can be expensive."

The men were divided into four groups based on their blood testosterone levels.

Those men in the highest quarter of testosterone readings -- with at least 19.6 nanomoles of the hormone per liter of blood -- had a 41 percent lower risk of dying over 10 years than those in the lowest quarter of testosterone readings -- less than 12.5 nanomoles of testosterone per liter of blood.

One major question is whether low testosterone is a risk factor itself or just a marker for other risk factors, said Dr. Victor Montori, associate professor of medicine at the Mayo Clinic in Rochester, Minn. He has done his own studies on testosterone replacement therapy.

"It does not mean that replacing or normalizing levels of testosterone would reverse the outcome," he said. "There are other hormones in the blood that are related to other risk factors, such as diabetes and hypertension."

In any case, a testosterone replacement regimen "would not be a walk in the park," Montori said. "It would be a major intervention."

According to Dr. Jorge Plutzky, director of the Vascular Disease Prevention Program at Brigham and Women's Hospital in Boston, the experience of women taking hormone replacement therapy (HRT) shows that hormonal regimens can have their dangers.

Beginning in the 1990s, millions of older American women took HRT, which replaced two female hormones, estrogen and progestin. Early trials had indicated that the therapy might reduce the risk of cardiovascular diseases such as heart attack and stroke in older women.

Instead, the Women's Health Initiative, a major study released in 2002, found that women taking HRT were at increased incidence of stroke, blood clots and breast cancer, noted Plutzky, who is also a spokesman for the American Cancer Society. HRT prescriptions dropped off precipitously after the study's release.

So, much more research is needed on the link between testosterone levels and mortality before doctors can recommend the regimen to men, Khaw said. Such studies might provide "insights and better understanding of disease mechanisms, such as how and why testosterone might be related to poorer health through, for example, insulin metabolism, lipid metabolism or inflammation," she said.

More information
There's more on testosterone at the U.S. National Library of Medicine.

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