Saturday, July 08, 2006

Eurixor, an unfermented aqueous extract of Viscum album L. harvested from poplar trees

Eurixor, an unfermented aqueous extract of Viscum album L. harvested from poplar trees, is reportedly standardized to contain a specific amount of one of mistletoe’s lectins (i.e., the lectin ML-I; see History section). Reviewed in [52] Some proponents contend the choice of extract should depend on the type of tumor and the gender of the patient.[76] Reviewed in [52,55,77] Mistletoe extracts are usually given by subcutaneous injection, although administration by other routes (i.e., oral and intrapleural) has been described.[27,36,42,45,46,51,57-59,65,66,76-94] Reviewed in [52,53,55,56,60,75] In most reported studies, subcutaneous injections were given 2 to 3 times a week, but the overall duration of treatment varied considerably. Viscum album is listed in the Homeopathic Pharmacopoeia of the United States (HPUS), which is the officially recognized compendium for homeopathic drugs in this country.[95]

Although the US Food and Drug Administration (FDA) has regulatory authority over homeopathic drugs, this authority is usually not exercised unless the drugs are formulated for injection or there is evidence of severe toxicity. At present, the FDA does not allow the importation or distribution of injectable preparations of mistletoe, including homeopathic formulations, except for the purpose of clinical research. The FDA has not approved the use of mistletoe as a cancer treatment.

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